Article
Lack of association between glutathione S-transferase M1 and T1 gene polymorphisms and susceptibility to preeclampsia: An updated systematic review and meta-analysis.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2020
Sljivancanin Jakovljevic Tamara, Jacimovic Jelena, Nikolic Nadja, Milasin Jelena
Abstract excerpt
Insufficient response to oxidative stress in placenta is proposed as a contributing factor for preeclampsia (PE) development. Glutathione S-transferases (GST) have significant role in detoxification processes. Conflicting results were published by several research groups regarding GST T1 and GST M1 deletion polymorphism as risk factors for PE. The aim of the present meta-analysis was to get a better understanding...
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