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Article

Hybrid phenotype mining method for investigating off-target protein and underlying side effects of anti-tumor immunotherapy.

BMC medical informatics and decision making - 9 Jul 2020

Zheng Yuyu, Meng Xiangyu, Zweigenbaum Pierre, Chen Lingling, Xia Jingbo

Abstract excerpt

BACKGROUND: It is of utmost importance to investigate novel therapies for cancer, as it is a major cause of death. In recent years, immunotherapies, especially those against immune checkpoints, have been developed and brought significant improvement in cancer management. However, on the other hand, immune checkpoints blockade (ICB) by monoclonal antiboties may cause common and severe adverse reactions (ADRs), the...

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Identifiers

PMID: 32646421
DOI: 10.1186/s12911-020-1105-4
PMCID: PMC7346346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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