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Article

Treatment of MEK inhibitor‐induced paronychia with doxycycline

9 Jul 2020

Abstract excerpt

A 12-year-old girl with neurofibromatosis type 1 and a large facial plexiform neurofibroma had been participating in a selumetinib clinical trial for the past 5 years. Despite decreased tumor size, she developed recalcitrant selumetinib-induced paronychia. Various antibiotics, topical medications, and surgeries were only minimally effective. Full-dose doxycycline resolved the paronychia, and sub-antimicrobial...

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PMID: 32644232
DOI: 10.1111/pde.14276

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