Article
Detection of Carbapenemase and CTX-M Encoding Genes Directly from Bronchoalveolar Lavage Using the CRE and ESBL ELITe MGB Assays: Toward Early and Optimal Antibiotic Therapy Management of Critically Ill Patients with Pneumonia.
Microbial drug resistance (Larchmont, N.Y.) - 1 Feb 2021
Boattini Matteo, Bianco Gabriele, Iannaccone Marco, Zanotto Elisa, Sidoti Francesca, Almeida André, De Rosa Francesco Giuseppe, Cavallo Rossana, Costa Cristina
Abstract excerpt
The detection of carbapenemase extended-spectrum β-lactamase (ESBL)-producing Enterobacterales (EB) has become a major issue among critically ill patients, especially due to their impact on appropriate antimicrobial therapy. This study aimed at evaluating the potential contribution of molecular assays to early optimization of empirical antibiotic therapy among critically ill patients with carbapenemase- and/or...
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