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Article

Pulsed electrical stimulation benefits wound healing by activating skin fibroblasts through the TGFβ1/ERK/NF-κB axis.

Biochimica et biophysica acta - 1 Jul 2016

Wang Yongliang, Rouabhia Mahmoud, Zhang Ze

Abstract excerpt

BACKGROUND: Dermal fibroblasts activated by conductive polymer-mediated electrical stimulation (ES) have shown myofibroblast characteristics that favor wound healing. However, the signaling pathway related to this phenotype switch remains unclear, and the in vivo survival of the electrically activated cells has never been studied. METHODS: Primary human skin fibroblasts were exposed to pulsed-ES mediated through...

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PMID: 27040591
DOI: 10.1016/j.bbagen.2016.03.023

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