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Article

Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder

6 Jul 2020

Abstract excerpt

BACKGROUND: Oxytocin is an important neuromodulator involved in cognition and socio-emotional processing that exerts its central activities via oxytocin receptors. Epigenetic alterations in the oxytocin receptor gene (OXTR) may be a molecular mechanism in the pathogenesis of obsessive-compulsive disorder (OCD). This study investigated the association between OXTR DNA methylation and the OCD status of a Korean...

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PMID: 32631409
DOI: 10.1186/s13148-020-00890-w

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