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Article

Genetic risks of schizophrenia identified in a matched case-control study.

European archives of psychiatry and clinical neuroscience - 1 Jun 2021

Oishi Kengo, Niitsu Tomihisa, Kanahara Nobuhisa, Sato Yasunori, Iwayama Yoshimi, Toyota Tomoko, Hashimoto Tasuku, Sasaki Tsuyoshi, Takase Masayuki, Shiina Akihiro, Yoshikawa Takeo, Iyo Masaomi

Abstract excerpt

It has been suggested that dopaminergic neurotransmission plays important roles for the psychotic symptoms and probably etiology of schizophrenia. In our recent preliminary study, we demonstrated that the specific allele combinations of dopamine-related functional single nucleotide polymorphisms (SNPs), rs10770141, rs4680, and rs1800497 could indicate risks for schizophrenia. The present validation study involved...

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PMID: 32623490
DOI: 10.1007/s00406-020-01158-3

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