Article
Evolution of a plant gene cluster in Solanaceae and emergence of metabolic diversity.
eLife - 2 Jul 2020
Fan Pengxiang, Wang Peipei, Lou Yann-Ru, Leong Bryan J, Moore Bethany M, Schenck Craig A, Combs Rachel, Cao Pengfei, Brandizzi Federica, Shiu Shin-Han, Last Robert L
Abstract excerpt
Plants produce phylogenetically and spatially restricted, as well as structurally diverse specialized metabolites via multistep metabolic pathways. Hallmarks of specialized metabolic evolution include enzymatic promiscuity and recruitment of primary metabolic enzymes and examples of genomic clustering of pathway genes. Solanaceae glandular trichomes produce defensive acylsugars, with sidechains that vary in...
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