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An epidemic CC1-MRSA-IV clone yields false-negative test results in molecular MRSA identification assays: a note of caution, Austria, Germany, Ireland, 2020

25 Jun 2020

Abstract excerpt

We investigated why a clinical meticillin-resistant Staphylococcus aureus (MRSA) isolate yielded false-negative results with some commercial PCR tests for MRSA detection. We found that an epidemic European CC1-MRSA-IV clone generally exhibits this behaviour. The failure of the assays was attributable to a large insertion in the orfX /SCC mec integration site. To ensure the reliability of molecular MRSA tests, it...

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PMID: 32613938
DOI: 10.2807/1560-7917.es.2020.25.25.2000929

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