Article
Study of angiopoietin and plasminogen genes in hereditary angioedema.
Revista da Associacao Medica Brasileira (1992) - 1 Apr 2020
Kruk Tatielly, Chong-Neto Herberto José, Dias Marina Mendonça, Campos Wagner Narciso, Moreno Adriana Santos, Mikami Liya Regina, Ferrari Lilian Pereira, Arruda Luísa Karla de Paula, Rosário Filho Nelson
Abstract excerpt
OBJECTIVE: To investigate the presence of the Angiopoietin 1 (ANGPT1) and Plasminogen (PLG) mutations in patients with Hereditary Angioedema (HAE) and normal C1 esterase inhibitor (C1-INH) levels, who do not harbor the F12 gene mutation. METHODS: Patients clinically diagnosed with HAE but without C1-INH deficiency or dysfunction and F12 gene mutation were evaluated. DNA extraction, quantification, and dilution...
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