Article
Genetic Study of Hereditary Angioedema Type I and Type II (First Report from Iranian Patients: Describing Three New Mutations).
Immunological investigations - 1 Jan 2022
Nabilou Susan, Pak Fatemeh, Alizadeh Zahra, Fazlollahi Mohammad Reza, Houshmand Masoud, Ayazi Maryam, Mohammadzadeh Iraj, Bemanian Mohammad Hasan, Fayezi Abbas, Nabavi Mohammad, Saghafi Shiva, Mohammadian Sajedeh, Kokhaei Parviz, Moin Mostafa, Pourpak Zahra
Abstract excerpt
BACKGROUND: Hereditary Angioedema (HAE) is a rare autosomal dominant immunodeficiency disease with mutation in C1 inhibitor gene (SERPING1) which deficient and dysfunction of C1-INH protein result in HAE type I or type II, respectively. The present study aimed to define the genetic spectrum of HAE type I and type II among Iranian patients. METHODS: Thirty-four patients with clinical phenotype of recurrent...
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