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Which genotype of Helicobacter pylori-cagA or cagE-Is better associated with gastric Cancer risk? Lessons from an extremely high-risk area in Iran.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020

Bakhti Seyedeh Zahra, Latifi-Navid Saeid, Gholizade Tobnagh Shokufe, Yazdanbod Kiana, Yazdanbod Abbas

Abstract excerpt

The association of the H. pylori cagA- /cagE-positive genotypes with the risk of gastric cancer (GC) in Ardabil-a high-risk area in North-West Iran-was assessed. Genotyping was performed in DNA from fresh gastric biopsies (N = 218). Occurrence of H. pylori infection was 85.32% (186/218). The total frequency of the cagA+vs. cagA-, cagE+vs. cagE-, cagA+/cagE-vs. AGCs (all genotype combinations), cagA-/cagE+vs....

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PMID: 32565361
DOI: 10.1016/j.meegid.2020.104431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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