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Article

AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL 1 High-Risk Genotype.

Journal of the American Society of Nephrology : JASN - 1 Aug 2020

Wu Huijuan, Larsen Christopher P, Hernandez-Arroyo Cesar F, Mohamed Muner M B, Caza Tiffany, Sharshir Moh'd, Chughtai Asim, Xie Liping, Gimenez Juan M, Sandow Tyler A, Lusco Mark A, Yang Haichun, Acheampong Ellen, Rosales Ivy A, Colvin Robert B, Fogo Agnes B, Velez Juan Carlos Q

Abstract excerpt

BACKGROUND: Kidney involvement is a feature of COVID-19 and it can be severe in Black patients. Previous research linked increased susceptibility to collapsing glomerulopathy, including in patients with HIV-associated nephropathy, to apo L1 (APOL1) variants that are more common in those of African descent. METHODS: To investigate genetic, histopathologic, and molecular features in six Black patients with COVID-19...

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Share to Acute Kidney Injury
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32561682
DOI: 10.1681/ASN.2020050558
PMCID: PMC7460910

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