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Article

Diagnostic assay to assist clinical decisions for unclassified severe combined immune deficiency

17 Jun 2020

Abstract excerpt

Key Points 3D organoid T-cell differentiation from a few hundred peripheral blood CD34+ cells was successfully achieved. 3D organoid T-cell differentiation could help physicians distinguish intrinsic from extrinsic defects underlying a clinical SCID phenotype.

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Identifiers

PMID: 32556280
DOI: 10.1182/bloodadvances.2020001736

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