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Article

Identification of PIGU as the Hub Gene Associated with KRAS Mutation in Colorectal Cancer by Coexpression Analysis.

DNA and cell biology - 1 Sept 2020

Zhang Meng, Wang Hai-Zhou, Li Hai-Ou, Zhou Yun-Jiao, Peng Ru-Yi, Liu Jing, Zhao Qiu

Abstract excerpt

Colorectal cancer (CRC) patients with KRAS mutation are refractory and usually have poor prognosis. We aimed to identify the hub gene associated with KRAS mutant CRCs. Weighted gene coexpression network analysis (WGCNA) was used to calculate the key module and the hub genes in GSE39582. Combined with the protein-protein interaction (PPI) network and survival analysis, the real hub gene was identified and further...

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Identifiers

PMID: 32552000
DOI: 10.1089/dna.2020.5574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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