Article
Weighted gene coexpression network analysis identifies hub genes related to KRAS mutant lung adenocarcinoma.
Medicine - 7 Aug 2020
Dai Dongjun, Shi Rongkai, Han Shuting, Jin Hongchuan, Wang Xian
Abstract excerpt
The aim of current study was to use Weighted Gene Coexpression Network Analysis (WGCNA) to identify hub genes related to the incidence and prognosis of KRAS mutant (MT) lung adenocarcinoma (LUAD).We involved 184 stage IIB to IV LUAD samples and 59 normal lung tissue samples from The Cancer Genome Atlas (TCGA) database. The R package "limma" was used to identify differentially expressed genes (DEGs). WGCNA and...
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