Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi

15 Jun 2020

Abstract excerpt

The work described here further elucidates how microorganisms sense and adapt to changes in their environment to establish infections in the human host. Specifically, we uncover a novel mechanism by which an opportunistic human fungal pathogen, Cryptococcus neoformans , responds to increases in extracellular pH in order to survive and thrive within the relatively alkaline environment of the human lung. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Carbohydrate Chemistry and Synthesis
Share to Fungal Infections and Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32546619
DOI: 10.1128/mbio.00719-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sterol-Response Pathways Mediate Alkaline Survival in Diverse FungiPMID 32546619Read ↗

pH Signaling in Human Fungal Pathogens: a New Target for Antifungal StrategiesSemantic proximity Read ↗

Internalization of the host alkaline pH signal in a fungal pathogenSemantic proximity Read ↗

pH Response Pathways in Fungi: Adapting to Host-derived and Environmental SignalsSemantic proximity Read ↗

Malassezia responds to environmental pH signals through the conserved Rim/Pal pathwaySemantic proximity Read ↗

Malassezia responds to environmental pH signals through the conserved Rim/Pal pathwaySemantic proximity Read ↗

Nutrient and Stress Sensing in Pathogenic YeastsSemantic proximity Read ↗

How human pathogenic fungi sense and adapt to pH: the link to virulenceSemantic proximity Read ↗

The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.Semantic proximity Read ↗

The fungal pathogen Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetrySemantic proximity Read ↗

Coordinated regulation of pH alkalinization by two transcription factors promotes fungal commensalism and pathogenicitySemantic proximity Read ↗

Adaptation to environmental pH: integrating the Rim101 and calcineurin signal transduction pathways.Semantic proximity Read ↗

Role of Amino Acid Metabolism in the Virulence of Human Pathogenic FungiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.