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Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning

23 May 2020

Abstract excerpt

The human gut microbiome is a complex ecosystem that both affects and is affected by its host status. Previous metagenomic analyses of gut microflora revealed associations between specific microbes and host age. Nonetheless there was no reliable way to tell a host's age based on the gut community composition. Here we developed a method of predicting hosts' age based on microflora taxonomic profiles using a...

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PMID: 32534441
DOI: 10.1016/j.isci.2020.101199

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