Article
Generation of ZJUi003-A, an induced pluripotent stem cell line from a Wilson's disease patient carrying a c.180_181del mutation in ATP7B gene.
Stem cell research - 1 Jul 2020
Wang Jue, Su Jun, Gong Tingyu, Li Tongyu, Shen Jiaxi, Wang Hao, Xie Haiyang, Zhou Lin, Zheng Shusen, Liang Ping
Abstract excerpt
Wilson's disease (WD) is an inherited autosomal recessive disease, which is caused by the mutation of ATP7B gene encoding copper-transporting ATPase protein. The WD patients always suffer from the excessive copper deposition in the liver and other tissues because of the dysfunction of the copper-transporting ATPase protein. In this study, we generated a patient-specific induced pluripotent stem cell (iPSC) line...
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