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Discovery of direct-acting antiviral agents with a graphene-based fluorescent nanosensor

29 May 2020

Abstract excerpt

Direct-acting agents against viral components are considered as the most promising candidates for the successful antiviral therapeutics. To date, no direct-acting drugs exist for the treatment against dengue virus (DV) infection, which can develop into life-threatening diseases. RNA-dependent RNA polymerase (RdRp), an RNA virus-specific enzyme highly conserved among various viral families, has been known as the...

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PMID: 32523995
DOI: 10.1126/sciadv.aaz8201

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