Article
Evaluation of Clinical Practices Related to Variants of Uncertain Significance Results in Inherited Cardiac Arrhythmia and Inherited Cardiomyopathy Genes.
Circulation. Genomic and precision medicine - 1 Aug 2020
Muller Reka D, McDonald Thomas, Pope Kathleen, Cragun Deborah
Abstract excerpt
BACKGROUND: Increasing use of genetic tests have identified many variants of uncertain significance (VUS) in genes associated with inherited arrhythmias and cardiomyopathies. Evaluation of clinical practices, including medical management recommendations for VUS patients and their families, is important to prevent over- or under-treatment that may result in morbidity or mortality. The purpose of this study is to...
Topics
- Arrhythmias, Cardiac
- Cardiologists
- Cardiomyopathies
- Genetic Counseling
- Genetic Testing
- Genetic Variation
- Humans
- Internet
- Surveys and Questionnaires