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Article

Synergistic effects of piperlongumine and gemcitabine against KRAS mutant lung cancer.

Tumori - 1 Apr 2021

Ye Wu, Huang Qingdong, Tang Tingyu, Qin Guangyue

Abstract excerpt

OBJECTIVE: To determine the combined efficacy of piperlongumine and gemcitabine for treatment of KRAS mutant lung cancer. METHODS: The cell growth inhibition of piperlongumine, gemcitabine, and piperlongumine plus gemcitabine was measured by Cell Counting Kit‑8 assay and the combination index was calculated. In addition, the combined effects of piperlongumine and gemcitabine on cell apoptosis, reactive oxygen...

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Identifiers

PMID: 32515291
DOI: 10.1177/0300891620930789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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