Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic alterations caused by the mutation and overexpression of the Tmem135 gene.

Experimental biology and medicine (Maywood, N.J.) - 1 Nov 2020

Lee Wei-Hua, Bhute Vijesh J, Higuchi Hitoshi, Ikeda Sakae, Palecek Sean P, Ikeda Akihiro

Abstract excerpt

IMPACT STATEMENT: Mitochondria are dynamic organelles undergoing fission and fusion. Proper regulation of this process is important for healthy aging process, as aberrant mitochondrial dynamics are associated with several age-related diseases/pathologies. However, it is not well understood how imbalanced mitochondrial dynamics may lead to those diseases and pathologies. Here, we aimed to determine metabolic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebellum
Share to Hippocampus
Share to Metabolic Networks and Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metabolome

Share to Metabolomics

Share to Myocardium

Share to Principal Component Analysis

Share to Retinal Pigment Epithelium

Source

Open in PubMed Open full text

Identifiers

PMID: 32515224
DOI: 10.1177/1535370220932856
PMCID: PMC7787545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic alterations caused by the mutation and overexpression of the Tmem135 gene.PMID 32515224Read ↗

Mitochondria: dynamic organelles in disease, aging, and development.Semantic proximity Read ↗

The role of mitochondrial dynamics in diseaseSemantic proximity Read ↗

Disturbance of Mitochondrial Dynamics and Mitochondrial Therapies in AtherosclerosisSemantic proximity Read ↗

Mitochondrial Quality Control in Health and DiseaseSemantic proximity Read ↗

Mitochondrial dysfunction and its association with age-related disordersSemantic proximity Read ↗

Mitochondrial quality control pathways as determinants of metabolic healthSemantic proximity Read ↗

Quantifying Mitochondrial Dynamics in Patient Fibroblasts with Multiple Developmental Defects and Mitochondrial Disorders.Semantic proximity Read ↗

The Mighty Mitochondria Are Unifying Organelles and Metabolic Hubs in Multiple Organs of Obesity, Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes: An Observational Ultrastructure StudySemantic proximity Read ↗

Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologiesSemantic proximity Read ↗

Mitochondrial dynamics and mitochondrial quality controlSemantic proximity Read ↗

Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular AgingSemantic proximity Read ↗

Mitochondrial dynamics in cancer-induced cachexiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.