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Manipulation of epithelial integrity and mucosal immunity by host and microbiota‐derived metabolites

8 Jun 2020

Abstract excerpt

The human intestinal tract contains a large number of microbes, their metabolites, and potentially harmful food antigens. The intestinal epithelium separates the mucosa where immune cells are located from luminal microbes by expressing various factors that assemble into physical and chemical barriers. In addition to epithelial cells, immune cells are essential for enforcing mucosal barriers through production of...

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PMID: 32511746
DOI: 10.1002/eji.201948478

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