Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface

Abstract excerpt

The high infection rate of SARS-CoV-2 necessitates the need for multiple studies identifying the molecular mechanisms that facilitate the viral entry and propagation. Currently the potential extra-respiratory transmission routes of SARS-CoV-2 remain unclear. Using single-cell RNA Seq and ATAC-Seq datasets and immunohistochemical analysis, we investigated SARS-CoV-2 tropism in the embryonic, fetal and adult human...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ocular Diseases and Behçet’s Syndrome
• Share to Retinal and Optic Conditions
• Share to SARS-CoV-2 and COVID-19 Research