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Oxidase, Esterase, and KDR-Associated Pyrethroid Resistance in Culex quinquefasciatus Field Collections of Collier County, Florida

1 Mar 2020

Abstract excerpt

ABSTRACT In several insect species, resistance to pyrethroids and DDT (dichlorodiphenyltrichloroethane) is linked to point mutations in the voltage-gated sodium channel (VGSC) gene. Pyrethroid-based insecticides prolong the opening of sodium channels, causing paralysis known as a “knockdown” effect before mortality occurs. Point mutations in the VGSC gene result in decreased pyrethroid binding and reduced...

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PMID: 32497474
DOI: 10.2987/19-6850.1

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