Article
Modest Sodium Reduction Increases Circulating Short-Chain Fatty Acids in Untreated Hypertensives: A Randomized, Double-Blind, Placebo-Controlled Trial.
Hypertension (Dallas, Tex. : 1979) - 1 Jul 2020
Chen Li, He Feng J, Dong Yanbin, Huang Ying, Wang Changqiong, Harshfield Gregory A, Zhu Haidong
Abstract excerpt
High-sodium diet may modulate the gut microbiome. Given the circulating short-chain fatty acids (SCFAs) are microbial in origin, we tested the hypothesis that the modest sodium reduction would alter circulating SCFA concentrations among untreated hypertensives, and the changes would be associated with reduced blood pressure and improved cardiovascular phenotypes. A total of 145 participants (42% blacks, 19%...
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