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Article

Association between factor V Leiden mutation and recurrent pregnancy loss in the middle east countries: a Newcastle-Ottawa meta-analysis.

Archives of gynecology and obstetrics - 1 Aug 2020

Hamedi Bahareh, Feulefack Joseph, Khan Aiza, Sergi Consolato

Abstract excerpt

PURPOSE: Heritable thrombophilia is a category of genetic disorders of the coagulation cascade with the increasing risk of thrombus formation and recurrent pregnancy loss (RPL). Factor V Leiden (FVL) (R506Q) mutation is the most common genetic cause of deep venous thrombosis, but its association with RPL has been inconsistent in studies arising from non-Western countries. The present metanalysis was aimed to...

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PMID: 32472185
DOI: 10.1007/s00404-020-05610-6

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