Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of CD133 in human embryonic stem cell proliferation and teratoma formation

27 May 2020

Abstract excerpt

BACKGROUND: Pluripotent stem cells (PSCs), including human embryonic stem cells (hESCs), hold great potential for regenerative medicine and cell therapy. One of the major hurdles hindering the clinical development of PSC-based therapy is the potential risk of tumorigenesis. CD133 (Prominin 1, PROM1) is a transmembrane protein whose mRNA and glycosylated forms are highly expressed in many human cancer cell types....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32460847
DOI: 10.1186/s13287-020-01729-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of CD133 in human embryonic stem cell proliferation and teratoma formationPMID 32460847Read ↗

CD133, Stem Cells, and Cancer Stem Cells: Myth or Reality?Semantic proximity Read ↗

New emerging roles of CD133 in cancer stem cell: Signaling pathway and miRNA regulationSemantic proximity Read ↗

CD133 as a Marker for Cancer Stem Cells: Progresses and ConcernsSemantic proximity Read ↗

Unmasking the Deceptive Nature of Cancer Stem Cells: The Role of CD133 in Revealing Their SecretsSemantic proximity Read ↗

Somatic Stem Cell Marker Prominin‐1/CD133 Is Expressed in Embryonic Stem Cell–Derived ProgenitorsSemantic proximity Read ↗

Comparative genomics on PROM1 gene encoding stem cell marker CD133Semantic proximity Read ↗

Reviewing and Updating the Major Molecular Markers for Stem CellsSemantic proximity Read ↗

A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutationsSemantic proximity Read ↗

CD133 Expression Strongly Correlates with the Phenotype of Very Small Embryonic-/Epiblast-Like Stem Cells.Semantic proximity Read ↗

AC133 expression in human stem cellsSemantic proximity Read ↗

CD133: molecule of the momentSemantic proximity Read ↗

Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.