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Article

Evolution of Antimalarial Drug Resistance Markers in the Reservoir of Plasmodium falciparum Infections in the Upper East Region of Ghana.

The Journal of infectious diseases - 13 Oct 2020

Narh Charles A, Ghansah Anita, Duffy Michael F, Ruybal-Pesántez Shazia, Onwona Christiana O, Oduro Abraham R, Koram Kwadwo A, Day Karen P, Tiedje Kathryn E

Abstract excerpt

BACKGROUND: The majority of Plasmodium falciparum infections, constituting the reservoir in all ages, are asymptomatic in high-transmission settings in Africa. The role of this reservoir in the evolution and spread of drug resistance was explored. METHODS: Population genetic analyses of the key drug resistance-mediating polymorphisms were analyzed in a cross-sectional survey of asymptomatic P. falciparum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32459360
DOI: 10.1093/infdis/jiaa286
PMCID: PMC7982568

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