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Article

Comparison of Three Sequencing Panels Used for the Assessment of Tumor Mutational Burden in NSCLC Reveals Low Comparability.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2020

Heeke Simon, Benzaquen Jonathan, Hofman Véronique, Long-Mira Elodie, Lespinet Virginie, Bordone Olivier, Marquette Charles-Hugo, Delingette Hervé, Ilié Marius, Hofman Paul

Abstract excerpt

INTRODUCTION: Tumor mutational burden (TMB) has been proposed as a novel predictive biomarker for the stratification of patients with NSCLC undergoing immune checkpoint inhibitor (ICI) treatment. The assessment of TMB has recently been established using large targeted sequencing panels, and numerous studies are ongoing to harmonize TMB assessment. "Correlation" or the coefficient of determination has generally...

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PMID: 32450274
DOI: 10.1016/j.jtho.2020.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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