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Article

Evolution of the Insecticide Target Rdl in African Anopheles Is Driven by Interspecific and Interkaryotypic Introgression.

Molecular biology and evolution - 1 Oct 2020

Grau-Bové Xavier, Tomlinson Sean, O'Reilly Andrias O, Harding Nicholas J, Miles Alistair, Kwiatkowski Dominic, Donnelly Martin J, Weetman David

Abstract excerpt

The evolution of insecticide resistance mechanisms in natural populations of Anopheles malaria vectors is a major public health concern across Africa. Using genome sequence data, we study the evolution of resistance mutations in the resistance to dieldrin locus (Rdl), a GABA receptor targeted by several insecticides, but most notably by the long-discontinued cyclodiene, dieldrin. The two Rdl resistance mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32449755
DOI: 10.1093/molbev/msaa128
PMCID: PMC7530614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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