Article
Donor-Derived Cell-Free DNA Testing in Solid Organ Transplantation: A Value Proposition
2 Apr 2020
Abstract excerpt
BACKGROUND: There is a need to improve personalized immunosuppression in organ transplantation to reduce premature graft loss. More efficient biomarkers are needed to better detect rejection, asymptomatic graft injury, and under-immunosuppression. Assessment of minimal necessary exposure to guide tapering and to prevent immune activation is also important. Donor-derived cell-free DNA (dd-cfDNA) has become...
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