Article
C-Fiber Loss as a Possible Cause of Neuropathic Pain in Schwannomatosis.
International journal of molecular sciences - 18 May 2020
Farschtschi Said C, Mainka Tina, Glatzel Markus, Hannekum Anna-Lena, Hauck Michael, Gelderblom Mathias, Hagel Christian, Friedrich Reinhard E, Schuhmann Martin U, Schulz Alexander, Morrison Helen, Kehrer-Sawatzki Hildegard, Luhmann Jan, Gerloff Christian, Bendszus Martin, Bäumer Philipp, Mautner Victor-Felix
Abstract excerpt
Schwannomatosis is the third form of neurofibromatosis and characterized by the occurrence of multiple schwannomas. The most prominent symptom is chronic pain. We aimed to test whether pain in schwannomatosis might be caused by small-fiber neuropathy. Twenty patients with schwannomatosis underwent neurological examination and nerve conduction studies. Levels of pain perception as well as anxiety and depression...
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