Evolution of virulence-related phenotypes of Sporothrix brasiliensis isolates from patients with chronic sporotrichosis and acquired immunodeficiency syndrome.

doi:10.1007/s42770-020-00297-y

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Article

Evolution of virulence-related phenotypes of Sporothrix brasiliensis isolates from patients with chronic sporotrichosis and acquired immunodeficiency syndrome.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] - 1 Mar 2021

Cruz Ingrid Ludmila Rodrigues, Freitas Dayvison Francis Saraiva, de Macedo Priscila Marques, Gutierrez-Galhardo Maria Clara, do Valle Antonio Carlos Francesconi, Almeida Marcos de Abreu, Coelho Rowena Alves, Brito-Santos Fábio, Figueiredo-Carvalho Maria Helena Galdino, Zancopé-Oliveira Rosely Maria, Almeida-Paes Rodrigo

Abstract excerpt

Sporotrichosis in immunocompromised patients has a high morbidity and may cause deaths. Particularly, patients with acquired immunodeficiency syndrome (AIDS) with low T CD4 counts develop a chronic disease, with severe and widespread forms. Recently, the ability of Sporothrix brasiliensis, the main agent of zoonotic sporotrichosis, to increase its virulence in a diabetic patient without HIV infection was...

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PMID: 32440844
DOI: 10.1007/s42770-020-00297-y
PMCID: PMC7966698

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