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Article

3D Bioprinting of osteochondral tissue substitutes - in vitro-chondrogenesis in multi-layered mineralized constructs.

Scientific reports - 19 May 2020

Kilian David, Ahlfeld Tilman, Akkineni Ashwini Rahul, Bernhardt Anne, Gelinsky Michael, Lode Anja

Abstract excerpt

For the generation of multi-layered full thickness osteochondral tissue substitutes with an individual geometry based on clinical imaging data, combined extrusion-based 3D printing (3D plotting) of a bioink laden with primary chondrocytes and a mineralized biomaterial phase was introduced. A pasty calcium phosphate cement (CPC) and a bioink based on alginate-methylcellulose (algMC) - both are biocompatible and...

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Identifiers

PMID: 32427838
DOI: 10.1038/s41598-020-65050-9
PMCID: PMC7237416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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