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Article

A Systematic and Comprehensive Review on Disease-Causing Genes in Amyotrophic Lateral Sclerosis.

Journal of molecular neuroscience : MN - 1 Nov 2020

Srinivasan E, Rajasekaran R

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder and is characterized by degeneration and axon loss from the upper motor neuron, that descends from the lower motor neuron in the brain. Over the period, assorted outcomes from medical findings, molecular pathogenesis, and structural and biophysical studies have abetted in providing thoughtful insights underlying the importance of disease-causing...

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PMID: 32415434
DOI: 10.1007/s12031-020-01569-w

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