Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene.

doi:10.1161/JAHA.119.015289

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Article

Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene.

Journal of the American Heart Association - 18 May 2020

Poller Wolfgang, Haas Jan, Klingel Karin, Kühnisch Jirko, Gast Martina, Kaya Ziya, Escher Felicitas, Kayvanpour Elham, Degener Franziska, Opgen-Rhein Bernd, Berger Felix, Mochmann Hans-Christian, Skurk Carsten, Heidecker Bettina, Schultheiss Heinz-Peter, Monserrat Lorenzo, Meder Benjamin, Landmesser Ulf, Klaassen Sabine

Abstract excerpt

Background Variants of the desmosomal protein desmoplakin are associated with arrhythmogenic cardiomyopathy, an important cause of ventricular arrhythmias in children and young adults. Disease penetrance of desmoplakin variants is incomplete and variant carriers may display noncardiac, dermatologic phenotypes. We describe a novel cardiac phenotype associated with a truncating desmoplakin variant, likely causing...

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Identifiers

PMID: 32410525
DOI: 10.1161/JAHA.119.015289
PMCID: PMC7660888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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