Article
An Innovative Lipidomic Workflow to Investigate the Lipid Profile in a Cystic Fibrosis Cell Line.
Cells - 12 May 2020
Dei Cas Michele, Zulueta Aida, Mingione Alessandra, Caretti Anna, Ghidoni Riccardo, Signorelli Paola, Paroni Rita
Abstract excerpt
Altered lipid metabolism has been associated to cystic fibrosis disease, which is characterized by chronic lung inflammation and various organs dysfunction. Here, we present the validation of an untargeted lipidomics approach based on high-resolution mass spectrometry aimed at identifying those lipid species that unequivocally sign CF pathophysiology. Of n.13375 mass spectra recorded on cystic fibrosis bronchial...
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