Article
Chromosome and Plasmid Features of Two ST37 Clostridioides difficile Strains Isolated in China Reveal Distinct Multidrug Resistance and Virulence Determinants.
Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2020
Liu Junyan, Peng Liang, Su Heng, Tang Haixian, Chen Dingqiang, Xu Zhenbo, Wu Aiwu
Abstract excerpt
Clostridioides difficile ST37 is an emerging and prevalent multilocus sequence type and represents a lineage of clinical significance. This study aimed to characterize two epidemic C. difficile ST37 strains, CD161 and CDT4. CD161 acquires a chromosome and two distinct plasmids, pCD161-L, sharing high similarity with Clostridium phage, and pCD161-S, while CDT4 has a chromosome and a plasmid pCDT4 identical to...
Topics
- Anti-Bacterial Agents
- China
- Clostridioides difficile
- Drug Resistance, Multiple, Bacterial
- Humans
- Microbial Sensitivity Tests
- Multilocus Sequence Typing
- Mutation
- Plasmids
- Ribotyping