Complement Pathways in Membranous Nephropathy: Complex and Multifactorial

Abstract excerpt

Membranous nephropathy (MN) is a rare, but severe autoimmune kidney disease and a major cause of nephrotic syndrome in adults. Clinically defined by nephrotic syndrome, which is persistent in approximately two-thirds of untreated patients, it manifests histologically by subepithelial immune deposits at the glomerular basement membrane in the kidney containing IgGs.

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