Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.

doi:10.1002/cjp2.171

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Article

Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.

The journal of pathology. Clinical research - 1 Oct 2020

Roseweir Antonia K, Park James H, Hoorn Sanne Ten, Powell Arfon Gmt, Aherne Susan, Roxburgh Campbell Sd, McMillan Donald C, Horgan Paul G, Ryan Elizabeth, Sheahan Kieran, Vermeulen Louis, Paul James, Harkin Andrea, Graham Janet, Sansom Owen, Church David N, Tomlinson Ian, Saunders Mark, Iveson Tim J, Edwards Joanne

Abstract excerpt

Histological 'phenotypic subtypes' that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I-III colorectal cancer (CRC) pilot cohort. However, clinical utility has not yet been validated. Therefore, this study assessed prognostic value of these subtypes in additional patient cohorts along with associations with risk of...

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PMID: 32401426
DOI: 10.1002/cjp2.171
PMCID: PMC7578335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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