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Article

Next-generation sequencing and histological response assessment in peritoneal metastasis from pancreatic cancer treated with PIPAC.

Journal of clinical pathology - 1 Jan 2021

Nielsen Malene, Graversen Martin, Ellebæk Signe Bremholm, Kristensen Thomas Kielsgaard, Fristrup Claus, Pfeiffer Per, Mortensen Michael Bau, Detlefsen Sönke

Abstract excerpt

BACKGROUND: Peritoneal metastasis from pancreatic cancer (PM-PC) may be treated with repeated pressurised intraperitoneal aerosol chemotherapy (PIPAC). Utility of next-generation sequencing (NGS) to detect cancer-related mutations in peritoneal quadrant biopsies (QBs) and peritoneal fluid (PF) after systemic and PIPAC treatment has not been evaluated. Around 90% of pancreatic cancers (PCs) harbour a KRAS...

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Source

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Identifiers

PMID: 32385139
DOI: 10.1136/jclinpath-2020-206607
PMCID: PMC7788484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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