Article
Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis.
Alimentary pharmacology & therapeutics - 1 Jun 2020
Carlsson Björn, Lindén Daniel, Brolén Gabriella, Liljeblad Mathias, Bjursell Mikael, Romeo Stefano, Loomba Rohit
Abstract excerpt
BACKGROUND: Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD) characterised by liver fat accumulation, inflammation and progressive fibrosis. Emerging data indicate that genetic susceptibility increases risks of NAFLD, NASH and NASH-related cirrhosis. AIMS: To review NASH genetics and discuss the potential for precision medicine approaches to treatment. METHOD:...
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