Article
Porcine DNAJB6 promotes PCV2 replication via enhancing the formation of autophagy in host cells.
Veterinary research - 7 May 2020
Han Cong, Du Qian, Zhu Lei, Chen Nannan, Luo Le, Chen Qiao, Yin Jiatong, Wu Xingchen, Tong Dewen, Huang Yong
Abstract excerpt
Hsp40/DnaJ family proteins play important roles in the infection process of various viruses. Porcine DNAJB6 (pDNAJB6) is a major member of this family, but its role in modulating the replication of porcine circovirus type 2 (PCV2) is still unclear. In the present study, pDNAJB6 was found to be significantly upregulated by PCV2 infection, and confirmed to be interacted with PCV2 capsid (Cap) protein and...
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