Article
Vitamin D receptor polymorphisms are associated with severity of wheezing illnesses and asthma exacerbations in children.
The Journal of steroid biochemistry and molecular biology - 1 Jul 2020
Leiter Katharine, Franks Kimberley, Borland Meredith L, Coleman Laura, Harris Leesa, Le Souëf Peter N, Laing Ingrid A
Abstract excerpt
Single nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene have shown linkage and association with asthma development in multiple cohort studies. However, the majority of investigations have focused on asthma phenotypes in cohorts with stable disease. We investigated the relationship between VDR SNPs and the frequency and severity of acute episodes of wheeze/asthma in a cohort of Australian...
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