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Article

Differentiating esophageal sensitivity phenotypes using pH-impedance in intensive care unit infants referred for gastroesophageal reflux symptoms.

Pediatric research - 1 Feb 2021

Jadcherla Sudarshan R, Sultana Zakia, Hasenstab-Kenney Kathryn A, Prabhakar Varsha, Gulati Ish K, Di Lorenzo Carlo

Abstract excerpt

BACKGROUND: To identify esophageal sensitivity phenotypes relative to acid (SAcid), bolus (SBolus), acid and bolus (SAcid+Bolus), and none (SNone) exposures in infants suspected with gastroesophageal reflux disease (GERD). METHODS: Symptomatic infants (N = 279) were evaluated for GERD at 42 (40-45) weeks postmenstrual age using 24-h pH-impedance. Symptom-associated probability (SAP) for acid and bolus components...

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Identifiers

PMID: 32375162
DOI: 10.1038/s41390-020-0930-6
PMCID: PMC7644596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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