Article
The human platelet alloantigen profile in blood donors from Amazonas, Brazil.
Transfusion medicine (Oxford, England) - 1 Dec 2016
Portela C N, Schriefer A, Albuquerque S R L, Perdomo R T, Parente A F A, Weber S S
Abstract excerpt
BACKGROUND: Human platelet antigens (HPAs) are alloantigens derived from polymorphisms in platelet-surface glycoproteins. The occurrence of alloantibodies against HPAs can lead to platelet destruction and subsequent thrombocytopenia. Brazilians have a high rate of racial admixture, and the knowledge of HPA polymorphisms in particular donors from north Brazil, who have a large Amerindian influence, is a relevant...
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