Article
Adipose-derived mesenchymal stem cells and extracellular vesicles confer antitumor activity in preclinical treatment of breast cancer.
Pharmacological research - 1 Jul 2020
Li Tao, Zhou Xiaohe, Wang Jingzhe, Liu Ziyao, Han Sen, Wan Lu, Sun Xiaochun, Chen Huabiao
Abstract excerpt
Both antitumor and protumor property of mesenchymal stem cells (MSCs) have been demonstrated. We hypothesize that this contradiction is due to the heterogeneity of MSC subsets and that extracellular vesicles (EVs) from distinct MSC subsets can transfer the corresponding antitumor activities. Here we evaluated the antitumor activities of two subsets of adipose-derived mesenchymal stem cells (ADSCs) and...
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