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Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity

20 Apr 2022

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) has revealed that adult white adipose tissue (WAT) harbors functionally diverse subpopulations of mesenchymal stromal cells that differentially impact tissue plasticity. To date, the molecular basis of this cellular heterogeneity has not been fully defined. Here, we describe a multilayered omics approach to dissect adipose progenitor cell heterogeneity in three dimensions:...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 35447091
DOI: 10.1016/j.cmet.2022.03.012

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